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Repressive histone modifications, such as histone hypoacetylation and hyperacetylation, further contribute to TSG silencing (Fahrner et al

Once recruited to the site of injury, rod microglia have the ability to degrade the extracellular matrix, to promote the retraction of dystrophic axons and to disrupt synapses, in a phenomenon known as synaptic stripping, decreasing synaptic activity and metabolic requirement of the damaged neurons (Perry and OConnor, 2010

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ZH and HX organized the methodology, investigation, and data collection

By employing scRNA-seq technology, researchers have identified these alterations at a single-cell level, revealing transcriptomic heterogeneity among several keratinocyte subpopulations during aging