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During rapid weight loss, however, demand may exceed endogenous synthesis capacity

VidalAlaball J, Butler C, CanningsJohn R, Goringe A, Hood K, McCaddon A, McDowell I, Papaioannou A

Am J Physiol 269:R1204R1212 Federici M, Porzio O, Lauro D et al (1998) Increased abundance of insulin/insulin-like growth factor-I hybrid receptors in skeletal muscle of obese subjects is correlated with in vivo insulin sensitivity