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Le Selank It acts as a positive allosteric modulator of GABA-A receptors, increasing the affinity of the GABA binding site without directly binding to the benzodiazepine site

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Consequently, the development of resistance by pathogenic fungi to any one of these drug classes would drastically narrow the range of available clinical treatment options

NICE guidance emphasises the importance of investigating the underlying cause of B12 deficiency rather than simply treating with supplements, as this may identify serious conditions requiring specific management