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Preclinical Studies Early preclinical studies in rodent obesity models demonstrated that AOD9604 administration reduced body weight and fat mass without affecting food intake, indicating a direct metabolic effect rather than an appetite-suppressing mechanism

E., McCaddon, A., & Williams, J

Low Risk of Side Effects Associated with hGH: Because AOD9604 is only a fragment of hGH, it does not bind to the hGH receptor to trigger insulin-like growth factor 1 (IGF-1) production, which is responsible for the anabolic (growth-promoting) and diabetogenic (insulin-resistance-inducing) effects of full hGH

In randomized controlled trials in people living with HIV and central fat accumulation, tesamorelin produced clinically meaningful reductions in visceral adipose tissue in a majority of patients and was associated with improvements in liver enzymes when deep abdominal fat decreased

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