MaP555-Alkyne (cell-permeable fluorogenic dye) Size:1mg Degrader building block for targeted

Degrader building block for targeted protein degradation

Contains an E3 ligase ligand substituted with piperidine

Product Name 2-[4-(2-aminoethyl)piperazin-1-yl]ethan-1-amine Synonyms Piperazine-1

HaloPROTACS: Use of Small Molecule PROTACs to Induce Degradation of HaloTag Fusion Proteins

Product Name Thalidomide-5'-piperidine-C1-alcohol Synonyms CAS Number 2229717-49-9 Related CAS Molecular Formula C19H21N3O5 Molecular Weight 371

MaP555-Alkyne (cell-permeable fluorogenic dye) Size:1mg Degrader building block for targetedMaP555 Alkyne is is a fluorogenic probe. MaP555 is a small molecule fluorogenic probe with excellent cell permeability. It is converted from 6 carboxytetramethylrhodamine (6 TAMRA) and has similar spectroscopic properties of 6 TAMRA. MaP555 has an acyl sulfamide structure which favors the spirolactam form, thus has excellent cell permeability. When the probe binds to its cellular targets, MaP555 mainly exists in the fluorescent zwitterion form. The