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Feng B, Wu J, Shen B, Jiang F, Feng J (2022) Cancer-associated fibroblasts and resistance to anticancer therapies, status, mechanisms, and countermeasures

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In drug intervention experiments, the traditional Chinese medicine Shenxianshengmai (SXSM) significantly up-regulates SHMT2 expression by activating the CaMKII-AC-PKA signaling cascade, thereby redirecting glutamine metabolism into the TCA cycle

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