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This complex process involves a series of sequential steps, beginning with the detachment of cancer cells from the primary tumor, followed by their migration through the extracellular matrix (ECM) and invasion into surrounding tissues and blood vessels

molecular ion mass) is required to utilize the high sensitivity MRM modes in TQ MS

Pediatrics 2001;108:776-89

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Here, the viral DNA is converted into covalently closed circular DNA (cccDNA), which serves as a template for transcription of the viral RNAs