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Table 1 Human studies of TMAO as a potential novel and independent risk factor for predicting clinical risk of atherosclerosis (AS) and prognostic stratification

Dec 25 2019;12(1)doi:10.3390/nu12010058 Chien YJ, Chang CY, Wu MY, Chen CH, Horng YS, Wu HC

71 Furthermore, studies have shown that the levels of PUFAs in young and middle-aged individuals are significantly correlated with neutrophil function

Lastly, while APOE effects dominated brain profiles, sex effects were more prominent in the periphery, which was also in accordance with a previous study in older (16 months old) APOE-TR mice (Shang et al., 2020), suggesting that regardless of age APOE has a major effect on brain bioenergetics