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The power of HTS in organoid-based drug discovery have been highlighted in cancer and to lesser extent in neurodegenerative diseases, such Alzheimers and Parkinsons (Krall et al., 2020

In this review, we specifically focus on known molecular and metabolic mechanisms linking skin epithelial cells and microorganisms in health and disease

Robson, Harvard University, United States Reviewed by Ionita Ghiran, Beth Israel Deaconess Medical Center and Harvard Medical School, United States Xinyu Song, Harvard Medical School, United States Tao Yu, Harvard Medical School, United States Updates Copyright 2025 Chen, Tang, Wang, Wang and Mao

Directly, the copper coordination prevents free copper-catalyzed Fenton reactions that generate hydroxyl radicals, while the peptide sequence itself can scavenge existing reactive oxygen species

Thus, histone lysine methylation can be associated with either activation or repression of transcription ultimately determined by the effectors