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HSV-2 tends to reactivate in the sacral ganglia (S2S4) and may cause pelvic or pudendal-type neuralgia with localized burning, hypersensitivity, or sharp pain in the genital or perineal region

Nature 614 , 762766 (2023)

Seek immediate medical attention if you experience any of the following while taking ibuprofen: Severe stomach pain or black, tarry stools Unexplained bruising or bleeding Dizziness, fainting, or rapid heartbeat Signs of allergic reaction, such as rash, swelling, or difficulty breathing Confusion, tremors, or unusual behavior (especially if on lithium or methotrexate) Even if symptoms are mild, consulting a healthcare professional can prevent complications

Similarly, since components may pass into breast milk, nursing mothers should consult their healthcare provider before starting treatment

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