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The cDNA was synthesised using the RevertAid First Strand cDNA Synthesis Kit (Thermo Scientific, #K1622) in a total volume of 10 l

In early Alzheimers disease (AD), excessive glycolysis leads to intracellular lactate accumulation, triggering excessive histone lactylation, amplifying glycolysis-related gene expression, and creating a feedback loop that exacerbates glucose metabolism in microglia [130]

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