michael-type acceptor reactivity toward glutathione Thiol-Michael addition based conjugate for activation and release Covalent Modifiers: A Chemical Perspective

Bioscience 27 , 454460 (1977)

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Methotrexate an old drug with new tricks

MicroRNA miR-212-5p, found at low levels in extracellular vesicles from injured brain tissues in TBI mice, has been identified as a negative regulator of PTGS2a key mediator of ferroptotic signalingsuggesting that miR-212-5p may confer neuroprotection by suppressing ferroptosis (227)

Glutathione Peroxidase 1 Promotes the Survival of Spiral Ganglion Neurons After Peroxynitrite Damage To clarify the role of GPX1 in the process of SGN injury caused by peroxynitrite, we performed experiments by increasing or inhibiting the expression of GPX1 in SGNs with the GPX1 mimic ebselen or using the gpx1 / mouse model