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Funding This work has been partially funded by the Spanish Ministry of Health, Instituto de Salud Carlos III (ISCIII), FIS PI14-01962, and the Andalusian Government grant BIO177 (FEDER funds of European Commission)

Sci Rep 16 , 18201 (2026)

Comparative Trials Head-to-head data suggest tirzepatide (Zepbound) achieved ~20.2% mean weight loss at 72 weeks versus ~13.7% with semaglutide (Wegovy)

facilitating mucosal healing at low concentrations while provoking dysbiosis and inflammation at elevated levels 50

Conventional medicine trims the weeds (blood pressure, sugar, proteinuria), but functional medicine enriches the soil improving energy, immunity, detoxification, sleep, and nutrition so the whole garden thrives again