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4.1.1 Local delivery of RNA-LNPs A straightforward way to bypass hepatic accumulation of LNPs is to change the administration route from intravenous delivery to other administration routes, which could shorten the delivery path and enhance accessibility to the target cells (Figure 3) (Chenthamara et al., 2019

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Studies were considered if they addressed rhamnetins pharmacological properties, molecular mechanisms, or therapeutic potential in cancer, including apoptosis, angiogenesis, EMT inhibition, oxidative stress, mitochondrial pathways, pharmacokinetics, or bioavailability