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Furthermore, at the tested concentration range (0.2 and 2.0 M), low binding to blood cells and preferential distribution into the plasma were observed with no concentration-dependency, in agreement with the in vivo results described above, and driven by high binding to plasma proteins

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Research has shown that AOD-9604 increases beta-3 adrenergic receptor expression in adipose tissue and enhances signaling through these receptors

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[DOI] [PMC free article] [PubMed] [Google Scholar] 413.Karkhaneh R, Faghihi H, Riazi-Esfahani H, Abrishami M, Bazvand F, Ebrahimiadib N, et al