diethyl maleate glutathione depletion 97 141-05-9 AOP-Wiki

AOP Wiki Depletion of hepatic glutathione and selective protein oxidation and inhibition of lipogenesis Stimulation of de novo glutathione synthesis by nitrofurantoin for enhanced resilience of hepatocytes Cell Biology and Toxicology Springer Nature Link The antioxidant glutathione plays a key role in protein folding The team discovered a few years ago that if glutathione levels aren't precisely maintained in mitochondria, all systems fail. On the heels The Depletion of Nuclear Glutathione Impairs Cell Proliferation in 3t3 Fibroblasts PLOS One

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