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Kiyoshi Okada, Hiroyuki Tanaka, Ko Temporin, Michio Okamoto, Yusuke Kuroda, Hisao Moritomo, Tsuyoshi Murase, Hideki Yoshikawa, Methylcobalamin increases Erk1/2 and Akt activities through the methylation cycle and promotes nerve regeneration in a rat sciatic nerve injury model, Experimental Neurology, Volume 222, Issue 2, April 2010, Pages 191-203 Tanaka, H

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Serious side effects are rare but should be reported to a healthcare provider immediately.

It works synergistically with folate in DNA synthesis and homocysteine metabolism

[10] NAD+ doesnt appear to adversely interact with common medications