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Description

Frequent epigenetic silencing of the folate-metabolising gene cystathionine-beta-synthase in gastrointestinal cancer

Nature clinical practice

12 ] In humans, melatonin production often declines with age, which may contribute to sleep disturbances and disruptions in normal biological timing

Comprehensive research on these interactions has increasingly revealed their complex and dynamic crosstalk, providing new insights into combined therapies targeting both metabolism and epigenetics and expanding available anticancer strategies