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As we age, our natural collagen production declines, leading to visible signs of aging such as wrinkles, sagging skin, and joint discomfort

This is because it supports mitochondrial function, which is essential for cellular energy production

Notably, a positive correlation exists between ChaC1 expression and immune infiltrating cells in corpus endometrial carcinoma (73)

Endometriosis is closely linked to iron overload, and these findings indicate that ectopic endometrial tissue, through repeated bleeding during its invasive growth, evolves into an iron-overloaded state under the influence of macrophages