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6AD and S7F), but not 3KE mutant, suggesting that GCLC succinylation level largely affects its enzymatic activity and further sensitivity of cancer cells to ferroptosis induction

These distinctive attributes underscore the potential of CAR expression on macrophages to enhance targeting and represent a viable avenue for immunotherapeutic interventions

Escape items such as fuses or keys should be second priority

Nature 518 , 417421 (2015)

A study (Wen et al., 2024) also showed that reducing the downregulation of the SIRT1/Nrf2/GPX4 pathway could increase the expression of SLC7A11 and inhibit ferroptosis in the hippocampus of splenectomized rats, thereby reducing the negative impact on cognitive function