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Recent studies have indicated that the absence of other amino acids, such as arginine, prevents cysteine depletion from triggering ferroptosis, highlighting the complementary roles of multiple amino acids in modulating iron-death [104]

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In hereditary hemochromatosis, downregulation of the cystine-glutamate transporter directly exacerbates ferroptosis-driven liver injury, while N-acetylcysteine supplementation restores glutathione levels and inhibits ferroptotic cell death [54]

Landmesser U, Cai H, Dikalov S, McCann L, Hwang J, Jo H, Holland SM, Harrison DG (2002) Role of p47(phox) in vascular oxidative stress and hypertension caused by angiotensin II

Effect of selenium and pentoxifylline on expression of CATSPER1 and 2 genes and FSH/LH levels in treated mice by dexamethasone