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As a result, these models also show altered synaptic properties, pyramidal neuron disinhibition, and impaired locomotor coordination, underscoring the critical role of the GAD67-PV + IN pathway in GABAergic transmission and motor control [31, 42, 43, 63,64,65]

Despite preventing steatosis, SCD1 knockout exacerbated hepatic fibrosis and cellular apoptosis in mice with NASH induced by a methionine and choline deficient diet [61]

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