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Unlike classical inflammation (characterized by heat, redness, and pain), neuroinflammation primarily involves the release of pro-inflammatory mediators (e.g., cytokines, chemokines, and ROS) by resident immune cells, particularly microglia, the CNSs innate immune effectors [110, 111]

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IV administration bypasses the digestive system completely , delivering a much higher, therapeutically potent dose directly into the bloodstream without risking stomach irritation, ensuring 100% bioavailability and comfort

While it is true that unprocessed licorice root can raise blood pressure, the licorice in my Leaky Gut Revive has had the component responsible for that effect removed