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Experimental studies in rat models have shown that the activity of the 20S proteasome decreases with age, which is accompanied not only by a reduction in its quantity but also by changes in the composition and structure of its subunits

This process occurs even in cells that are not infected with virus

95% CI: 1.1133.715

In light of this development, the process measure Application of Functional Assessment/Care Plan, ( which measures only whether a functional assessment is completed and a functional goal is included in the care plan, is no longer necessary, and can be replaced with a measure that evaluates the LTCH's outcome of care on a patient's function

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