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In a rat model of ischemic stroke, administration of the herbal compound Salvia miltiorrhiza extract modulated gut microbiota composition, reduced infarct size, and decreased markers of inflammation and oxidative stress, indicating a gut-mediated neuroprotective effect (Wu J

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TAMs are not fixed with irreversible phenotype and M2-like macrophages can be converted and polarized into the anti-tumoral macrophage, M1-like macrophage, with change in TIME by intervention due to its extreme plasticity 17,54

3 When participants' hair color was compared with their stress diaries, Dr