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Each phase is associated with distinct fitness costs and benefits

doi: 10.5694/j.1326-5377.1998.tb123402.x 7 HarwoodKVuguinPDiMartino-NardiJ

This suggests that, in clinical practice, HHI treatment is more often interrupted than permanently discontinued in response to AEs

It neutralises free radical damage, supports liver detoxification, and drives cellular repair

Because several genes such as Bcl2, MAPK8 , and NFKB1 were up-regulated after exposure to AFB1, therefore, it has suggested that apoptotic-associated responses to AFB1 exposure played a critical role in hepatotoxicity of this mycotoxin (310)