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Firstly, the Xc system (solute carrier family 7 member 11 and family 3 member 2 (SLC7A11 and SLC3A2)) is responsible for taking up cystine to generate the substrate cysteine for the synthesis of GSH and is also involved in the formation of the GPX4 catalytic unit

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S2CID 221504018

As a result, several important brain regions related to cognition were not included in our study, such as the hippocampus and dorsolateral prefrontal cortex