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Glycocalyx degradation usually begins in the SIRS stage, when proinflammatory factors (TNF-, IL-1) activate endothelial cells and directly destroy the components of the glycocalyx (such as HS, HA) by activating MMPs [23]

The AAFP advises that injectable therapy leads to more rapid improvement and should be considered in patients with severe deficiency or severe neurologic symptoms (Langan RC, Goodbred AJ, 2017)

Using the right biocide is important

It primarily works by stimulating the production of telomerase, an enzyme that helps maintain and repair telomeres, which are protective parts of DNA that deteriorate as we age

Understanding when to resume after surgery and how long before surgery to pause the compound is critical for safety