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MD, Age Related Macular Degeneration in Integrative Medicine (Fourth Edition), 2018 Diotallevi M, Checconi P, Palamara AT, Celestino I, Coppo L, Holmgren A, Abbas K, Peyrot F, Mengozzi M, Ghezzi P

Although curcumin is generally considered safe at dietary doses, but high systemic or long-term intake may cause gastrointestinal symptoms such as nausea, diarrhea, and abdominal discomfort (Hewlings and Kalman, 2017)

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Long-acting C-peptide and neuropathy in type 1 diabetes: a 12-month clinical trial