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HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia

Analysis in cells and organisms have established the essential importance of functional retrieval sub-domains for development and homeostasis, and disease-associated sub-domain dysregulation is associated with human disease 2,3,4,5

Interestingly, its unsaturated analogue, squalene, was included in the dataset and labeled as Floral and Oily, with no association to Fishy descriptors

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