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doi: 10.1186/rr175 8 RaghuG

Interrelated role of cigarette smoking, oxidative stress, and immune response in copd and corresponding treatments

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Mechanistic gaps in pathway crosstalk and causality: Current studies have primarily focused on individual pathways (e.g., Nrf2-mediated antioxidant defense and TGF-/SmadHDAC3-driven fibrosis) but lack insights into the core molecular hubs integrating these networks

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