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Serum copper reference range is 70 to 140 mcg/dL, and ceruloplasmin (the primary copper transport protein) is 20 to 35 mg/dL

Second, patients with chronic kidney disease (CKD) stages 3b through 5 may have impaired copper excretion through bile and urine [13]

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Clin Biochem 42:10321040 Al-Yafee YA, Al-Ayadhi LY, Haq SH, El-Ansary AK (2011) Novel metabolic biomarkers related to sulfur-dependent detoxification pathways in autistic patients of Saudi Arabia