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10.1007/s11689-011-9081-8 J

It can attenuate activity of the NMDA receptor (Majewska et al., 1990), enhance the uptake of glutamate from the synaptic cleft (Lane and Lawen, 2013), and directly inhibit calcium channels, thereby modulating neuronal excitability (Nelson et al., 2007)

Introduction Over one century ago, the discovery of insulin marked a transformative milestone in diabetes treatment, leading from life-saving animal-derived therapies to recombinantly synthetic human insulin and its analogues

This tumor, which was diagnosed as an anaplastic oligoastrocytoma (WHO grade III) that had progressed from a grade II tumor, exhibited FGFR1-TKDD positivity