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Funding: MJF was supported by T32 Funding from the University of Wisconsin Madison Medical Scientist Training Program from the National Institute of General Medical Sciences ( T32GM140935 and T32GM008692 and from the University of Wisconsin Microbes in Health and Disease from the National Institute of Allergy and Infectious Diseases ( Additional funding supporting this work was obtained from National Institute of Allergy and Infectious Diseases ( awarded to JDS as R01AI184369, R21AI173738 and R01AI137070

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Biomarkers for endothelial function, insulin sensitivity, intracellular signaling, maintaining DNA integrity , inflammation, metabolic flexibility, mitophagy (recycling old and damaged mitochondria) and cellular senescence (also called "zombie cells" as these cells have lost proper function, harm nearby cells and do not die off) are all improved

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