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The role of dietary polyphenols in tumor necrosis factor-related apoptosis inducing ligand (TRAIL)-induced apoptosis for cancer chemoprevention

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Hence, this review explores the association of CD44 variant exon expression with clinical outcomes of patients undergoing chemotherapy, highlights their role in key cell death pathways regulation, provides critical analysis of therapeutic substances and clinical studies targeting CD44 and discusses directions for further development of CD44 targeted therapeutic strategies

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