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Introduction Peripheral neuropathy (PN), a condition characterized by damage to the peripheral nerves, is a major clinical concern due to its prevalence and significant impact on patients quality of life [1,2,3]

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The resulting particles were subjected to non-uniform 3D refinement, followed by a final local Euler angle local refinement to generate the final consensus maps from which the -helical domain (AHD) of the G s protein and the detergent micelle were masked out