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Restoring NAD+ levels through therapy shows promise in addressing multiple aging signs at once, which highlights the value of NAD+ treatment strategies in longevity medicine

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Retatrutide's Phase 2a in MASH/MASLD (Sanyal et al., Nat Med 2024) reported approximately 86% relative reduction in liver fat content at 12 mg/week the strongest hepatic-fat data among the incretin class

ISSLS Prize Winner: Inhibition Of NF-b Activity Ameliorates Age-Associated Disc Degeneration In A Mouse Model Of Accelerated Aging