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In animal models, it has been reported that the activation of apoptosis in type II AEC promotes a fibrotic phenotype, for example, apoptotic cells may release cytokines and growth factors that recruit and activate fibroblasts, prompting them to secrete ECM, whereas inhibiting apoptosis helps to alleviate pulmonary fibrosis (102104)

(2018) review detailed the central position of the vagus nerve in the MGBA

320,321,322 Mechanistically, PRIMA-1 functions through its degradation product, the methylene quinuclidinone (MQ)

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In the present study, subcutaneous (s.c.) administration of reserpine at a dose of 1 mg/kg daily for 3 days was utilized