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1-3 On the computational side, we capitalized on our previous work, which provided solid and calibrated computational protocols based on the DFT-D3 method, for estimating stability constants of various [M 2+ :peptide/amino acid] complexes, as well as on recently developed protocols for exhaustive and efficient conformational sampling of peptides and macrocycles

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Clinically, it presents with severe and persistent retrosternal pain that is not fully relieved by nitrate medications or rest

Furthermore, studies have suggested that the therapeutic synergy between sitagliptin and metformin co-administration can increase mRNA and protein expression levels (Daneshjou et al., 2022)

For athletes with confirmed deficiency, this investment yields clear returns through restored performance capacity