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MPO plays an important role in inflammation and tissue damage (Lewis and Trempe 2017)

Johnson SC, Yanos ME, Kayser EB, et al

Can J Physiol Pharmacol 96(4):337344 Kang JS et al (2008) Role of CYP2E1 in thioacetamide-induced mouse hepatotoxicity

These actions are consequences of an active RAS protein which is GTP-bound, and dephosphorylation of GTP to GDP inactivates this protein [12,15]

Newton, I.L.G., Sheehan, K.B., Lee, F.J., Horton, M.A., and Hicks, R.D., Invertebrate systems for hypothesis-driven microbiome research, Microbiome Sci