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The mice were housed in standard laboratory cages, with a maximum of 5 animals per cage, under SPF conditions, with regulation of temperature (22C 1C) and humidity (55%) and a 12-h:12-h dark-light cycle, and were free to get food and water

Background Hattori et al [1] harvested the cells from the peritoneal fluid

Preclinical studies have shown that this peptide fragment can influence pathways associated with lipid metabolism and intracellular signalling without eliciting broad growth hormonemediated effects

Although it is well-known that cuprizone intoxication causes spongiform degeneration of the CNS [15], edema has been largely ignored, potentially because of the absence of massive BBB disruption in this model [8, 12, 30]

CLA isomeric blends at the same dose also showed no significant effects on plasma glucose or insulin levels in healthy human subjects [91]