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The systemic application of ROS scavengers, including phenyl-N-tert-butyl nitro and MnSOD, attenuates BTZ-induced mechanical hypersensitivity ( 3.1.2 Endoplasmic reticulum (ER) stress Defects in ER-associated degradation, unfolded protein responses, and ER stress have been implicated in various myelin disorders (Volpi et al., 2016)

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Yet, the oxidative folding step took up to 10 days for completion 25