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This has sparked pushback from the industry, with manufacturers launching court cases to challenge its decisions, some of which were successful

Interestingly, Filtered Clove Small Cigars are now being marketed as an alternative for tobacconists and consumers

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Diabetes was defined based on measured fasting plasma glucose (126 mg/dL), measured glycosylated hemoglobin (HbA1c 6.5%), self-reported prior diagnosis of diabetes, or current use of antidiabetic medications 22

Search methods A literature search was performed of all relevant information related to tobacco smoking, its effect on human sperm parameters, and its role as a mutagen