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PLoS ONE 10 , e0138032 (2015)

During the chronic progression of PD, non-apoptotic death pathways contribute even more substantially than apoptosis, and are closely intertwined with mitochondrial dysfunction

Sclerostin small-molecule inhibitors promote osteogenesis by activating canonical Wnt and BMP pathways

Thus, GSTP1 is a lactatebinding protein, the function of which is probably modulated in response to lactic acid levels that constitute, at least in part, a tumor metabolic micro-environment

393,394 For instance, miR-146a regulates inflammatory responses by targeting IRAK1 and TRAF6, and its decreased expression contributes to increased inflammation in DPN