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Although rupture of the plasma membrane represents the terminal event of ferroptotic death, emerging evidence indicates that ferroptotic signaling is initiated at intracellular membrane compartments, including the ER, Golgi-associated vesicles, and lysosomes 107-110

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29,30 Mercury ingestion forms vacuoles in the anterior capsule that migrate posteriorly and become aggregated, affecting the sodium-potassium pump (Na+/K+-ATPase) and resulting in a rapidly increasing nuclear sclerotic cataract