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4749 Given that claims and disclaimers were already present in current tobacco marketing, using a fictional brand could have undermined the relevance of our study to ongoing public health concerns about claims

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While the harm reduction theory behind a [VLN] cigarette that provides nicotine to smokers at non-addictive levels is easy to understand, the development of a high nicotine cigarette may seem counter-intuitive, said Sicignano

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