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Although ADCs with higher DARs have expectedly greater in vitro potency, preclinical studies suggest that they may be subject to more rapid hepatic clearing and a less favorable safety profile, eventually lowering their therapeutic index [18]

Energy metabolism shifts in GR-knockout Av

Notable examples include sulforaphane (SFN) from broccoli and phenethyl isothiocyanate (PEITC) from watercress (107)

Nrf2 improves endothelial function by resisting oxidative stress and mitochondrial damage, thereby delaying atherosclerosis (245)

The inner carboxyl terminal faces the cytoplasm and interacts with the cytoskeleton [5]