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The medicine is also advised to be used with caution in elderly patients (aged above 65 years) after consulting the doctor

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While some benefits have been observed in several studies for the various diseases and conditions discussed here, the side effects associated with anti-VEGF or anti-VEGFR-2 therapies can be severe and include heightened risk of arterial thromboembolic events, hypothyroidism, wound healing complications, GI perforations, neutropenia and hematological effects and increased risks for other cardiac adverse events (245, 247249)

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A specific quote comes from the consultation because protocols are individualized to the patient