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0.16 ng/ml/12 ml/day till the sacrifice) and intragastrically after cuprizone instilations, while controls received simultaneously drinking water only (12 ml/day) as well as an equivolume of saline (5 ml/kg) intragastrically after cuprizone instillations

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Escalating the dose of a single compound eventually hits diminishing returns or triggers dose-dependent side effects without proportional metabolic benefit

It is known for its anti-inflammatory and pain-relieving properties