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Common risk factors for developing shingles include: Older age, with the likelihood of getting shingles being 10 times higher in adults over the age of 60 compared to children younger than 10 Having a weakened immune system from taking immunosuppressant medications or due to conditions such as HIV and AIDS, certain cancers such as leukemia and lymphoma, severe psoriasis, and advanced psoriatic arthritis Having a family history of shingles Receiving a bone marrow transplant or solid organ transplant such as a heart transplant, kidney transplant, or liver transplant Taking medications that weaken the immune system such as steroids (also called corticosteroids or glucocorticoids), organ transplant rejection medicines, and chemotherapy drugs Experiencing severe psychological stress, which can weaken the immune system and allow the varicella-zoster virus to reactivate Is shingles contagious

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The mechanistic literature in this area is smaller than the fibroblast and wound healing literature but has been a consistent thread in the GHK-Cu research footprint

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